A new way to capture the brain’s electrical symphony

Biophysicist Adam Cohen was strolling around San Francisco, California, in 2010, when a telephone call caught him by surprise. “We have a signal,” said the caller. Nearly 5,000 kilometres away, in Cambridge, Massachusetts, his collaborators had struck gold. After months of failed experiments, the researchers had found a fluorescent protein that allowed them to watch signals as they passed between neurons.

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Nature 561, 300-302 (2018)

References

1. Kralj, J. M., Douglass, A. D., Hochbaum, D. R., Maclaurin, D. & Cohen, A. E. Nature Meth. 9, 90–95 (2012). ArticleGoogle Scholar
2. Piatkevich, K. D. et al.Nature Chem. Biol.14, 352–360 (2018) ArticlePubMedGoogle Scholar
3. Siegel, M. S. & Isacoff, E. Y. Neuron19, 735–741 (1997). ArticlePubMedGoogle Scholar
4. Xu, Y., Zou, P. & Cohen, A. E. Curr. Opin. Chem. Biol.39, 1–10 (2017). ArticlePubMedGoogle Scholar
5. Yang, H. H. et al.Cell166, 245–257 (2016). ArticlePubMedGoogle Scholar
6. Gong, Y. et al.Science350, 1361–1366 (2015) ArticlePubMedGoogle Scholar
7. Adam, Y. et al. Preprint at bioRxiv https://doi.org/10.1101/281618 (2018).
8. Chien, M.-P. et al. Preprint at bioRxiv https://doi.org/10.1101/211946 (2017).

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